Introduction to the Technical Application of Supercritical Extraction Device, Come and Collect!
The supercritical extraction device has a low critical temperature and is suitable for the extraction and purification of heat sensitive compounds. It can provide an inert environment, avoid product oxidation, and does not affect the Active ingredient of the extract. It is fast in extraction, nonflammable, safe in use, and does not pollute the environment.
The solvent strength of a supercritical fluid depends on the temperature and pressure at which it is extracted. Using this characteristic, only need to change the pressure and temperature of the extractant fluid, you can extract the different components in the sample according to the solubility in the fluid, and the weakly polar substances under low pressure are extracted first, with the increase of pressure, the substances with large polarity and large molecular weight and the basic properties, so supercritical extraction under program boost can obtain different extraction components, and at the same time can also play a role in separation.
The change of temperature is reflected in the two factors that affect the density of the extractant and the vapor pressure of the solute, in the low temperature region (still above the critical temperature), the temperature increases to reduce the fluid density, and the solute vapor pressure does not increase much, therefore, the temperature of the solubility of the extractant can make the solute precipitate from the fluid extractant, when the temperature is further increased to the high temperature area, although the density of the extractant is further reduced, but the solute vapor pressure increases, the volatility increases, and the extraction rate not only does not decrease but has a tendency to increase.
In addition to pressure and temperature, the addition of a small amount of other different solvents to a supercritical fluid can also change its ability to dissolve solutes. Its mechanism of action is not fully understood. Usually the amount of addition does not exceed 10%, and mostly polar solvents methanol, isopropanol, etc. By adding a small amount of polar solvent, the application of supercritical fluid extraction technology can be extended to more polar compounds.
The critical temperature of the supercritical extraction device is low, suitable for the extraction and purification of heat-sensitive compounds, can provide an inert environment, avoid product oxidation, do not affect the active ingredients of the extract, fast extraction speed, non-flammable, safe to use, and do not pollute the environment.
What are the technical applications of the supercritical extraction unit? Let's take a brief look at it together.
The characteristics of the supercritical extraction device determine its wide application. For example, in the pharmaceutical industry, it can be used for the extraction of active ingredients, the purification of heat-sensitive biologics and the separation of lipid mixtures; In the food industry, it can be used for the extraction of hops, the extraction of pigments, etc.; In the perfume industry, it can be used for the extraction of natural and synthetic fragrances; In the chemical industry, it can be used for the separation of mixtures, etc. The specific application of supercritical extraction device can be divided into the following aspects:
1. Extract, extract and isolate bioactive molecules from medicinal plants.
2. Lipids from different microorganisms for recovery of lipids or removal of lipids from sugars and proteins.
3. Extract anti-cancer active substances from a variety of different plants, especially paclitaxel obtained from yew bark and branches and leaves for the prevention and treatment of diseases.
4. Vitamins, mainly vitamin E extraction.
5. Analyze and purify various bioactive research substances (natural or synthetic), and remove us without using molecules (such as removing pesticides from vegetable extracts) or "residues" to obtain purification technology products.
6. Processing of various extracts with natural medicines, antibacterial or antioxidant substances, such as basil, red skewers, thyme, garlic, onions, paprika, licorice and fennel seeds.