Application of Supercritical carbon dioxide extraction in drug preparation

Supercritical carbon dioxide extraction refers to the method of separating and purifying carbon dioxide as an extractant at a temperature and pressure exceeding its critical temperature and pressure. Compared with traditional chemical solvents, there are many characteristics, such as: non-toxic, odorless, colorless, low cost, easy to recycle, environmental protection, etc.

Supercritical CO2 extraction

Due to the fact that carbon dioxide does not require heating in the extraction process and its unique physicochemical properties, it has a wide range of applications in many fields. For example, supercritical carbon dioxide extraction technology has important applications in plant extracts, pharmaceutical materials, food additives, cosmetics, in vitro diagnostic drugs, and the removal of environmental pollutants.

 

In plant extracts, supercritical carbon dioxide extraction can effectively extract the active ingredients contained in plants without destroying their chemical structure, and the quality of the extract is more stable. In pharmaceutical materials, supercritical carbon dioxide extraction can greatly reduce the residue of toxic and harmful substances, and the extracted medicinal materials are easier to absorb.

 

The environmentally friendly nature of supercritical carbon dioxide extraction has also received widespread attention. Compared with traditional solvent extraction methods, supercritical carbon dioxide extraction can reduce the pollution of harmful substances to the environment. At the same time, it is a natural resource that can be recycled and improve the efficiency of resource utilization.

 

In short, supercritical carbon dioxide extraction technology has become an important branch of modern industry. Driven by continuous technological innovation and development, the scope of application will be more widely promoted and developed.

 

Supercritical carbon dioxide extraction is currently a kind of extraction that is currently attracting attention worldwide. It is the process of separating, extracting and purifying carbon dioxide using the physical properties of carbon dioxide in the supercritical state. Compared to traditional extraction techniques, extraction has many advantages:

 

Non-toxic. Carbon dioxide is a non-toxic and harmless substance, which is not harmful to the environment and human body.

 

High efficiency. The ability to scan substances at fast speeds increases the efficiency of separation, extraction and purification. At the same time, it can also be reused, avoiding waste of resources and reducing costs.

 

Wide scope of application. Supercritical CO2 extraction is suitable for extracting substances with different properties, such as chemical, natural, biological, pharmaceutical, etc.

 

It can be seen that supercritical carbon dioxide extraction technology is of great significance in practical application and will play a positive role in the development of different fields. There are very wide applications in drug preparation, where the extraction of the active ingredients in natural medicines is of the utmost importance.

 

Traditional natural medicine extraction methods require large amounts of organic solvents, are time-consuming, costly, and unsafe. Supercritical CO2 extraction technology can avoid these shortcomings, effectively extract the active ingredients of the drug, and will not affect the drug itself.

 

Taking Chinese medicinal materials as an example, supercritical carbon dioxide extraction can ingest the active ingredients in white peony medicinal materials under high pressure and achieve the purpose of purification. In addition, it can also be used to extract active ingredients of air-dried lotus seeds, green tea and other medicinal herbs. In short, its application will greatly accelerate the process of drug research and development, improve the purity and efficiency of drugs, and have huge market value and development potential.

 

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